Filipp Peter Musculus was a physician resident on Dejima from 1738 to 1746. He had at least one child by a courtesan of the Maruyama, Michishio of the Nagato-ya.
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References
Gary Leupp, Interracial Intimacy in Japan: Western Men and Japanese Women, 1543-1900, A&C Black (2003), 123.
