- Born: 1488
- Died: 1537
- Sons: Uesugi Tomosada
- Distinction: Lord of Musashi
- Japanese: 上杉朝興 (Uesugi Tomooki)
Tomooki was the son of Uesugi Tomoyoshi. He made several attempts to resist the movement of the Hôjô into Musashi, starting with a failed attempt to relieve the Muira at Arai in 1517. He lost Edo castle in 1524 and spent the remainder of his life fighting with the Hôjô. He married a daughter to Takeda Harunobu, the eldest son of Takeda Nobutora, but she died soon after the marriage.
- Initial text from Sengoku Biographical Dictionary (Samurai-Archives.com) FWSeal & CEWest, 2005