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Tomooki was the son of [[Uesugi Tomoyoshi]]. He made several attempts to resist the movement of the [[Hojo clan|Hôjô]] into Musashi, starting with a failed attempt to relieve the [[Miura clan|Muira]] at [[Arai]] in [[1517]]. He lost [[Edo castle]] in [[1524]] and spent the remainder of his life fighting with the Hôjô. He married a daughter to [[Takeda Harunobu]], the eldest son of [[Takeda Nobutora]], but she died soon after the marriage.  

Tomooki was the son of [[Uesugi Tomoyoshi]]. He made several attempts to resist the movement of the [[Hojo clan|Hôjô]] into Musashi, starting with a failed attempt to relieve the [[Miura clan|Muira]] at [[Siege of Arai|Arai]] in [[1517]]. He lost [[Edo castle]] in [[1524]] and spent the remainder of his life fighting with the Hôjô. He married a daughter to [[Takeda Harunobu]], the eldest son of [[Takeda Nobutora]], but she died soon after the marriage.  

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