*1859 April [[James Hepburn]] sets sail from New York.
*1859 April [[James Hepburn]] sets sail from New York.
*1859/4/24 (May 26) [[Rutherford Alcock]] and his translator [[Kumano no Denkichi]] arrive in Edo harbor.
*1859/4/24 (May 26) [[Rutherford Alcock]] and his translator [[Kumano no Denkichi]] arrive in Edo harbor.
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*1859/4 to 1859/5 [[HMS Actaeon|HMS ''Actaeon'']] arrives at [[Tsushima han|Tsushima]] and its crew stay for a time at several villages on the island.
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*1859/4/17 to 1859/5/5 [[HMS Actaeon|HMS ''Actaeon'']] arrives at [[Tsushima han|Tsushima]] and its crew stay for a time at several villages on the island.
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*1859/5 HMS ''Actaeon'' calls at Pusan.
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*1859/5/9-25 HMS ''Actaeon'' calls at Pusan.
*1859/5 Rutherford Alcock takes up his post as the first British diplomatic representative in Japan.
*1859/5 Rutherford Alcock takes up his post as the first British diplomatic representative in Japan.
*1859/6 [[Yokohama]], [[Nagasaki]], and [[Hakodate]] are opened as [[treaty ports]].
*1859/6 [[Yokohama]], [[Nagasaki]], and [[Hakodate]] are opened as [[treaty ports]].