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*[[Udagawa Genzui]] completes ''[[Seisetsu Naika Senyo|Seisetsu Naika Sen'yô]]'', the first Japanese translation of a text on internal medicine.
 
*[[Udagawa Genzui]] completes ''[[Seisetsu Naika Senyo|Seisetsu Naika Sen'yô]]'', the first Japanese translation of a text on internal medicine.
 
*The [[Meirindo|Meirindô]] is established at [[Kanazawa castle]].
 
*The [[Meirindo|Meirindô]] is established at [[Kanazawa castle]].
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*The ''[[Sanshikan]]'' renders the ''shinsadame'' system of [[Ryukyu Kingdom|Ryukyuan]] court ranks permanent.
    
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