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*[[Sakamoto Ryoma|Sakamoto Ryôma]] flees [[Tosa han|Tosa]], joins up with pro-''[[sonno joi|sonnô jôi]]'' rebel groups in [[Edo]]; seeks to assassinate [[Katsu Kaishu|Katsu Kaishû]], ends up becoming one of Katsu's disciples instead.
 
*[[Sakamoto Ryoma|Sakamoto Ryôma]] flees [[Tosa han|Tosa]], joins up with pro-''[[sonno joi|sonnô jôi]]'' rebel groups in [[Edo]]; seeks to assassinate [[Katsu Kaishu|Katsu Kaishû]], ends up becoming one of Katsu's disciples instead.
 
*[[James Hepburn]] moves to Yokohama and opens a dispensary for the sick, also begins to preach Christianity.
 
*[[James Hepburn]] moves to Yokohama and opens a dispensary for the sick, also begins to preach Christianity.
*The shogunate relaxes ''[[sankin kotai|sankin kôtai]]'' obligations.
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*The shogunate relaxes ''[[sankin kotai|sankin kôtai]]'' obligations, and there is an exodus of samurai from the city.
 
*Japan's first diplomatic mission to England is dispatched, under [[Takenouchi Yasunori]]. While in London, the mission visits the 1862 World's Fair ([[Great London Exposition]]), the Japan pavilion at which was organized by [[Rutherford Alcock]] without any official [[Tokugawa shogunate|bakufu]] involvement.
 
*Japan's first diplomatic mission to England is dispatched, under [[Takenouchi Yasunori]]. While in London, the mission visits the 1862 World's Fair ([[Great London Exposition]]), the Japan pavilion at which was organized by [[Rutherford Alcock]] without any official [[Tokugawa shogunate|bakufu]] involvement.
 
*[[Charles Wirgman]]'s ''[[Japan Punch]]'' is first issued.
 
*[[Charles Wirgman]]'s ''[[Japan Punch]]'' is first issued.
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